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L
8 几个月前

I recently came across a fantastic company with a ...

I recently came across a fantastic company with a great website! Their products are amazing and have made a significant difference in my life. I can't recommend them enough. Keep up the good work!

O
11 几个月前

Eidos therapeutics is doing an amazing job in deli...

Eidos therapeutics is doing an amazing job in delivering high-quality products. Their website has all the necessary information, and their customer support is exceptional. I'm glad I found them!

B
11 几个月前

👍 Eidos therapeutics is doing a fantastic job! The...

👍 Eidos therapeutics is doing a fantastic job! Their website is incredibly informative and easy to navigate. The products they offer are top-notch, and the customer service is outstanding. I'm very impressed with their commitment to quality.

X
1年以前

I'm really impressed with the efforts of Eidos the...

I'm really impressed with the efforts of Eidos therapeutics. The website is easy to use, and their products are of average quality. The service they provide is commendable. Keep up the good work!

A
1年以前

Eidos therapeutics has been a great company to dea...

Eidos therapeutics has been a great company to deal with. Their website is easy to navigate and has all the information I need. Their products have made a positive impact on my health. I couldn't be happier!

D
1年以前

Eidos therapeutics is a reliable company with a us...

Eidos therapeutics is a reliable company with a user-friendly website. I have been a customer for over a year now, and I must say that their products are exceptional. The team is always ready to help and provide guidance. Highly recommended!

B
1年以前

I recently discovered a company with an amazing we...

I recently discovered a company with an amazing website. Their products are of excellent quality and have greatly improved my health. I cannot thank them enough. I highly recommend their products to everyone seeking a positive change in their life.

S
1年以前

I'm really impressed with the quality products and...

I'm really impressed with the quality products and services provided by Eidos therapeutics. Their website is easy to use, and the team is always helpful in answering any questions. Highly recommended!

P
1年以前

I recently came across a company with an informati...

I recently came across a company with an informative website. Their products are above average in quality and have made a difference in my life. I'm grateful for their commitment to customer satisfaction.

A
1年以前

As a customer, I must say that Eidos therapeutics ...

As a customer, I must say that Eidos therapeutics is an excellent company. Their website is user-friendly and provides all the necessary information about their products. The products I bought from them have greatly improved my health. I highly recommend Eidos therapeutics to everyone!

关于Eidos therapeutics

Eidos Therapeutics:解决转甲状腺素蛋白淀粉样变性中未满足的需求

Eidos Therapeutics 是一家临床阶段的生物制药公司,致力于开发针对转甲状腺素蛋白淀粉样变性(ATTR)引起的疾病的创新疗法。该公司成立于 2013 年,此后一直在不懈努力,以解决该领域日益增长的未满足需求。

转甲状腺素蛋白淀粉样变性是一种罕见的进行性疾病,会影响多个器官,包括心脏、神经和消化系统。当称为淀粉样蛋白的异常蛋白质在身体组织和器官中积聚时,就会发生这种情况,导致器官功能障碍和衰竭。有两种类型的 ATTR:遗传性 ATTR (hATTR) 和野生型 ATTR (wtATTR)。 hATTR 是由影响转甲状腺素蛋白产生的基因突变引起的,而 wtATTR 是自发发生的,没有任何已知的遗传原因。

尽管是一种罕见疾病,但由于其高发病率,ATTR 已成为药物开发的一个越来越重要的重点领域。目前可用的治疗方法只能缓解症状,而不能解决疾病的根本原因。这就是 Eidos Therapeutics 的用武之地。

该公司的主要候选产品是 AG10,这是一种口服小分子,旨在稳定转甲状腺素蛋白并防止其错误折叠成淀粉样蛋白。 AG10 在临床前研究和 1 期临床试验中显示出可喜的结果。在这些试验中,AG10 的耐受性良好,未报告严重不良事件。

Eidos Therapeutics 最近完成了名为 ATTRibute-CM 的 AG10 3 期临床试验的注册。该试验旨在评估 AG10 与安慰剂相比在尚未接受 TTR 稳定剂或基因沉默疗法治疗的 hATTR 心肌病(一种影响心脏的 hATTR 形式)患者中的安全性和有效性。

除了 AG10,Eidos Therapeutics 还针对 wtATTR 以及其他形式的 hATTR,例如多发性神经病(PN)和家族性淀粉样神经病(FAP),开发了其他候选产品。

除了其创新的管道外, Eidos Therapeutics 还拥有一支经验丰富的专业团队,他们热衷于改变患者的生活。公司的领导团队包括来自辉瑞公司、默克公司、基因泰克公司等顶级制药公司的经验丰富的高管。

总之,Eidos Therapeutics 处于开发由转甲状腺素蛋白淀粉样变性引起的疾病的新疗法的前沿。到目前为止,其主要候选产品 AG10 显示出令人鼓舞的结果,它有望成为患有这种虚弱疾病的患者的游戏规则改变者。随着 Eidos 疗法在这一领域的不断研究,我们可以期待更多的突破,随着时间的推移,这将有助于显着改善患者的治疗效果!

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Eidos therapeutics

Eidos therapeutics

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