I have been using Magenta Therapeutics' services for a while now and they have never disappointed. Their team is highly knowledgeable and always available to assist me. The quality of their service is outstanding and their website is user-friendly. Highly recommended!
I have had an amazing experience with Magenta Therapeutics. Their team is highly professional and skilled. They have a deep understanding of the industry and provide innovative solutions. I am glad I found them and will continue to work with them in the future.
😃 I can't express how satisfied I am with Magenta Therapeutics. The level of professionalism and dedication they have shown is truly remarkable. They have helped me overcome various challenges in my business. I am grateful for their support. 😃
I recently had the pleasure of working with Magenta Therapeutics and it was truly an amazing experience. Their team members are highly professional and knowledgeable. They go above and beyond to deliver exceptional service. The company truly values its customers and takes the time to understand their needs. I highly recommend Magenta Therapeutics to anyone looking for top-notch services in the industry.
I have been using their services for a while now and I am really impressed. The quality of their work is outstanding and their team is always helpful. They provide timely and accurate solutions to any issues or questions I have. Highly recommended!
I have been using their services for quite some time now and I must say, I am extremely satisfied. Magenta Therapeutics provides outstanding and reliable service. Their team is always prompt, efficient, and professional. The website is user-friendly and easy to navigate. They have truly exceeded my expectations. I would highly recommend their services to anyone in need.
👌 Magenta Therapeutics is a game-changer in the industry. They have revolutionized the way we approach our work. Their services are outstanding and their team is highly skilled and efficient. I highly recommend them to anyone seeking reliable solutions. 👌
I have been a customer of Magenta Therapeutics for a while now and I am extremely happy with their services. Their team is always responsive, knowledgeable, and friendly. The quality of their work is exceptional. Highly recommended!
Magenta Therapeutics has been a great partner for my business. Their expertise in the industry is unmatched. They have consistently provided excellent service and support. I highly recommend them to anyone looking for a reliable and trustworthy company.
👍 Magenta Therapeutics is truly an amazing company. Their services are top-notch and their team is highly skilled. They always go the extra mile to ensure customer satisfaction. I have been a loyal customer for years and have never been disappointed. Keep up the good work! 👍
Magenta Therapeutics 是一家临床阶段的生物技术公司，致力于开发能够利用干细胞移植的疗效并让更多患者受益的疗法。该公司由一群经验丰富的科学家和企业家于 2016 年创立，他们认识到干细胞疗法在改变严重疾病治疗方面的潜力。
Magenta Therapeutics 的使命是通过使其更安全、更有效和更容易获得来彻底改变干细胞移植。干细胞移植目前用于治疗一系列血液疾病，包括白血病、淋巴瘤和镰状细胞病。然而，该过程可能有风险且复杂，需要高剂量的化学疗法或放射疗法来为患者的身体进行移植做准备。
Magenta Therapeutics 旨在通过开发可提高干细胞移植安全性和有效性的新疗法来克服这些挑战。该公司的方法涉及使用称为“调节剂”的小分子，可以选择性地靶向骨髓中的特定细胞，同时避免其他组织受到损害。与传统预处理方案相比，这种靶向预处理方法已在临床前研究中显示可降低毒性并提高植入率。
除了在调理剂方面的工作外，Magenta Therapeutics 还在开发可以增强干细胞治疗潜力的新型基因疗法。其中一种疗法涉及使用 CRISPR/Cas9 基因编辑技术来修饰造血干细胞 (HSC)，使其对化疗或辐射损伤具有抵抗力。这可以让因年龄或健康状况不符合传统移植手术条件的血液病患者获得这种挽救生命的治疗选择。
Magenta Therapeutics 取得重大进展的另一个领域是通过其名为“干细胞动员”的专有平台扩大干细胞移植的可及性。该平台使用称为 CXCR2 拮抗剂的小分子，临床前研究表明，这些小分子增加了 HSC 从骨髓转移到外周血循环的能力，在外周血循环中可以轻松收集它们，而无需像骨髓抽吸这样的侵入性操作。
自五年前成立以来，Magenta Therapeutics 已经取得了几个里程碑。 2018 年，它在纳斯达克上市，股票代码为 MGTA，筹集了 1 亿美元，这使他们能够扩大研究计划，进一步加快开发管道进入商业化阶段； 2020 年，他们宣布了评估 MGTA-145 加 plerixafor 动员方案的 II 期临床试验的积极结果，展示了强大的动员 HSCs 健康捐助者；最近（2021 年 6 月），他们公布了 I/II 期研究的积极中期数据，该研究评估了 MGTA-117 CD117 靶向抗体药物偶联物 (ADC)，专为同种异体移植前的靶向耗竭 HSC 而设计。
总体而言，Magenta Therapeutics 为寻求接触尖端生物技术公司的投资者提供了一个令人兴奋的机会，这些公司专注于通过基因编辑技术等创新方法改善人类健康结果，并结合针对白血病淋巴瘤镰状细胞性贫血等造血系统疾病的先进药物发现平台除其他外，同时扩大获得治愈能力的干细胞移植在全球范围内增加了更多患者，无论年龄或健康状况传统上与此类医疗干预相关的限制
magentatx.com
