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安大略省大脑研究所：开创性的大脑研究、商业化和护理
人脑是人体中最复杂、最迷人的器官之一。它控制着我们的思想、情绪、动作和感官。然而，它也容易受到影响我们生活质量的各种疾病和障碍的影响。这就是安大略脑研究所 (OBI) 成立的原因 - 以推进安大略省的大脑研究、商业化和护理。
OBI 是一个非营利组织，成立于 2010 年，其使命是通过创新研究、合作和知识转化来改善脑部疾病患者的生活。该研究所汇集了来自安大略省各地的研究人员、临床医生、行业合作伙伴和患者，以加速发现，从而更好地治疗脑部疾病。
研究
OBI 工作的核心是研究——探索新的方法来理解大脑的工作原理以及当它不能正常工作时会出现什么问题。该研究所资助的前沿研究项目专注于广泛的神经系统疾病，例如阿尔茨海默病、帕金森病、癫痫、多发性硬化症 (MS)、创伤性脑损伤 (TBI)、抑郁症和焦虑症。
OBI 资助研究的一个例子是 Tom Mikkelsen 博士关于多形性胶质母细胞瘤 (GBM) 的项目，这是一种治疗选择有限的侵袭性脑癌。 Mikkelsen 博士旨在通过使用先进的测序技术分析他们的基因图谱，为 GBM 患者开发个性化疗法。
另一个例子是 Elizabeth Finger 博士关于亨廷顿病 (HD) 的项目，亨廷顿病是一种影响运动控制和认知功能的遗传疾病。 Finger 博士使用磁共振成像 (MRI) 等神经成像技术来研究 HD 患者大脑随时间的变化。
商品化
OBI 不仅支持基础科学，还帮助将科学发现转化为实际应用，通过分拆公司或许可协议等商业化活动直接或间接地造福患者。该研究所拥有一支敬业的业务发展专业团队，他们与研究人员和行业合作伙伴密切合作，以确定有前途的技术并将其推向市场。
OBI 商业化努力的一个成功例子是创建一家名为 Winterlight Labs 的衍生公司，该公司使用自然语言处理 (NLP) 技术开发用于认知障碍的数字生物标记。 Winterlight Labs 由 Frank Rudzicz 博士创立，他是一位 OBI 资助的研究人员，专门研究 NLP 和机器学习。
关心
OBI 认识到，在改善大脑健康方面，研究和商业化只是方程式的一部分。该研究所还专注于通过促进知识转化来加强患者护理——将研究成果转化为可供临床医生、患者、护理人员和政策制定者使用的实用工具和资源的过程。
OBI 实现这一目标的一种方式是通过其综合发现计划 (IDP)，该计划将研究人员、临床医生和患者聚集在一起，共同为 MS 或 TBI 等特定脑部疾病创建解决方案。 IDPs 使用以患者为中心的方法，强调不同利益相关者之间的协作，以确保研究结果具有相关性、可访问性和可操作性。
OBI 促进知识转化的另一种方式是通过其 Brain-CODE 平台——一个在线数据库，用于存储来自临床试验、影像学研究或基因分析等各种来源的大脑相关数据。 Brain-CODE 允许研究人员在保护患者隐私的同时安全地彼此共享数据。这种协作方法使研究人员能够访问比他们自己无法访问的更大的数据集，从而有助于加速发现。
结论
安大略省大脑研究所是一个世界级的组织，汇集了不同的利益相关者以追求一个共同的目标：改善所有安大略人的大脑健康。通过其创新研究项目、商业化活动和知识转化计划，OBI 正在为安大略省成为脑科学领域的全球领导者做出重大贡献。无论您是寻找资助机会的研究人员，还是寻求更好治疗方法的患者，安大略脑研究所都是可以帮助您实现目标的宝贵资源。
braininstitute.ca
