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Sphere Fluidics Limited：利用微流体 Pico 液滴技术革新单细胞分析
Sphere Fluidics Limited 是一家领先的生物技术公司，专门开发基于微流控微滴技术的自动化高通量单细胞分析平台。该公司的创新解决方案使研究人员能够以前所未有的精度、速度和效率分析和分离单个细胞，为药物发现、诊断和个性化医疗开辟了新的可能性。
Sphere Fluidics 由来自剑桥大学和伦敦帝国理工学院的微流体、生物化学和工程学专家团队于 2010 年创立，迅速成为单细胞分析领域的先驱。其专有技术平台将先进的微细加工技术与尖端成像系统和生物信息学工具相结合，能够每天快速筛选数百万个细胞。
Sphere Fluidics 技术的核心是其获得专利的微滴发生器芯片。这种微型设备每秒可以产生数百万个大小均匀的液滴，将单个细胞或颗粒包裹起来。每个液滴都充当微型反应容器，可以使用荧光显微镜、PCR 扩增或 CRISPR 基因编辑等各种技术独立分析或操作。
Sphere Fluidics 提供多种基于其 picodroplet 技术平台的产品：
1) Cyto-Mine®：用于高通量单细胞分析和单克隆抗体发现的集成系统。 Cyto-Mine® 将皮滴生成与荧光激活细胞分选 (FACS) 相结合，每天可筛选多达 4000 万个细胞以获得所需的表型或功能。
2) ADEPT™：一种使用皮滴进行 DNA 组装和蛋白质表达优化的自动化系统。 ADEPT™ 可在几分钟而不是几天内将多个 DNA 片段组装到质粒中，从而实现基因构建体的快速原型制作。
3) SpheroID™：一个 3D 细胞培养平台，使用皮滴从单个细胞中创建大小均匀的球体或微组织。 SpheroID™ 允许研究人员在体外模拟体内组织的复杂性和异质性，从而实现更准确的药物测试和毒性筛选。
Sphere Fluidics 的产品已被全球领先的学术机构、制药公司和生物技术初创公司采用。其技术已被广泛应用于抗体发现、细胞系开发、CRISPR 筛选、合成生物学和癌症研究等领域。
Sphere Fluidics 与竞争对手的不同之处在于它对自动化和集成的关注。通过将单细胞分析工作流程的多个步骤组合成使用皮滴作为载体的无缝过程，Sphere Fluidics 的系统可以实现无与伦比的通量，同时最大限度地减少人为错误和样品损失。这使得以高分辨率和可重复性筛选大型细胞或分子库成为可能。
除了其商业产品外，Sphere Fluidics 还为需要定制解决方案以满足其特定研究需求的客户提供定制服务。其经验丰富的科学家团队可以提供实验设计、分析开发、数据分析和生物信息学方面的咨询。
Sphere Fluidics 致力于通过不断创新和与客户的合作来推进单细胞分析领域的发展。它的愿景是为研究人员提供工具，使他们能够释放单个细胞在理解疾病机制和开发新疗法方面的全部潜力。
综上所述，
Sphere Fluidics Limited 是一家生物技术公司，专门从事基于微流体微微液滴技术的自动化高通量单细胞分析平台。该公司的创新解决方案使研究人员能够以前所未有的精度、速度和效率分析单个细胞，为药物发现、诊断、个性化医疗等开辟了新的可能性。拥有基于其获得专利的 picodroplet 技术平台的多种产品，包括 Cyto-Mine® ADEPT™ SpheroID™ 3D 细胞培养平台等； Sphere Fluidics 已成为单细胞分析领域的先驱。它对自动化和集成的关注使其从竞争对手中脱颖而出，从而能够以高分辨率和可重复性筛选大型细胞或分子库。 Sphere Fluidics 致力于通过不断创新和与客户的合作来推进单细胞分析领域的发展。
spherefluidics.com
