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M
8 几个月前

I recently had the pleasure of exploring a biotech...

I recently had the pleasure of exploring a biotech company's website, and I was thoroughly impressed with the innovative approach and dedication to advancing cancer immunotherapy. The website provided comprehensive information about the company's novel technologies and promising pipeline of product candidates, which left me feeling confident in their commitment to making a meaningful impact in the field of oncology. The clear presentation and user-friendly interface made navigating through the site a seamless and informative experience. Additionally, the testimonials and success stories shared on the website served as a testament to their impactful work. Overall, my visit to the website was both enlightening and inspiring, and I look forward to following this company's progress.

G
10 几个月前

I recently used a biotech company for a research p...

I recently used a biotech company for a research project and I'm beyond impressed. The team was outstanding and provided excellent guidance. I would highly recommend their services to others!

D
12 几个月前

I had a fantastic experience with a biotech compan...

I had a fantastic experience with a biotech company recently! They were extremely knowledgeable and efficient. The customer service was excellent. I would highly recommend their services!

H
1年以前

I had a wonderful experience working with a biotec...

I had a wonderful experience working with a biotech company recently. The team was very knowledgeable and professional. They provided excellent guidance and support throughout the project. I would highly recommend their services!

C
1年以前

I used a biotech company for a project and they de...

I used a biotech company for a project and they delivered exceptional results. The team was efficient and professional. I would definitely recommend their services for any research needs.

J
1年以前

Turnstone Biologics is an amazing company! They ha...

Turnstone Biologics is an amazing company! They have a great team and provide top-notch services. I was impressed with their expertise and the quality of their work. I would definitely recommend them to others.

I
1年以前

I had a really great experience with Turnstone Bio...

I had a really great experience with Turnstone Biologics. The team was extremely knowledgeable and helpful. They were able to answer all of my questions and provide great guidance throughout the process. I would highly recommend them to anyone!

P
1年以前

I recently used a biotech company for a research p...

I recently used a biotech company for a research project and I was very satisfied with their services. The team was professional and efficient, and they delivered excellent results. I would definitely recommend their services to others.

关于Turnstone biologics

Turnstone Biologics:通过病毒免疫疗法革新癌症治疗

癌症是影响全世界数百万人的最具破坏性的疾病之一。尽管癌症治疗取得了重大进展,但仍需要更有效的疗法来改善患者的预后和生活质量。 Turnstone Biologics 是一家生物技术公司,旨在通过开发下一代病毒免疫疗法来彻底改变癌症治疗。

Turnstone Biologics 成立于 2015 年,迅速确立了自己在病毒免疫治疗领域的领先地位。公司的使命是利用病毒的力量抗击癌症,为患者提供更好的治疗选择。凭借其尖端技术和创新方法,Turnstone Biologics 吸引了来自世界各地的顶尖人才,并与领先的制药公司建立了合作伙伴关系。

Turnstone Biologics 方法的核心是其称为 VacTide ™的专有平台技术。该技术将溶瘤病毒 (OV) 与肿瘤特异性 T 细胞相结合,以产生针对癌细胞的强大免疫反应。 OV 是天然存在或经过基因改造的病毒,可以选择性地感染和杀死癌细胞,同时不伤害健康细胞。肿瘤特异性 T 细胞是根据癌细胞表面存在的特定标记物或抗原识别和攻击癌细胞的免疫细胞。

通过将 OV 与肿瘤特异性 T 细胞相结合,VacTide™ 产生协同效应,可增强针对癌症的免疫反应。 OV 感染并杀死癌细胞,将肿瘤抗原释放到血液中。这些抗原然后激活肿瘤特异性 T 细胞,这些细胞识别并攻击全身任何剩余的癌组织。

Turnstone Biologics 的管道包括几个基于其 VacTide ™平台技术的有前途的候选人。主要候选药物 Ad-MG1-MAGEA3 靶向 MAGE-A3 阳性实体瘤,如非小细胞肺癌 (NSCLC)、黑色素瘤、头颈鳞状细胞癌 (HNSCC)、膀胱癌 (BC)、卵巢癌 (OC)、三阴性乳腺癌 (TNBC) 等。

Ad-MG1-MAGEA3 在临床前研究中显示出可喜的结果,它可以诱导强烈的抗肿瘤反应,而不会在携带来自患者样本的人类肿瘤的动物模型中引起显着的毒性或不良反应。

除了 Ad-MG1-MAGEA3 候选表达 MAGE-A3 抗原的实体瘤;其他候选者包括针对 HSV-2 阳性癌症的 Ad-REP-HSV2,例如多形性胶质母细胞瘤 (GBM); Ad-REP-CMV靶向CMV阳性癌症,如多形性胶质母细胞瘤(GBM); Ad-REP-EBOV 靶向表达埃博拉病毒糖蛋白的癌症;目前处于不同阶段的开发中,包括临床前研究到 I/IIa/IIb/III 期临床试验,涵盖全球多种适应症。

Turnstone Biologics 对创新的承诺超越了其科学研究工作;它还包括对患者护理和宣传的坚定奉献。该公司与患者团体和倡导者密切合作,以确保其疗法满足他们的需求,同时倡导支持所有患者获得创新治疗的政策,无论其社会经济地位或地理位置如何。

总之,Turnstone Biologics 代表了肿瘤学研究的一个令人兴奋的新前沿,它利用病毒的力量来对抗某些类型的癌症,使用 VacTide ™平台技术等新方法,该技术结合了溶瘤病毒 (OV) 和肿瘤特异性 T 细胞 (TST) ).在全球多个适应症中有几个有前途的候选药物正在开发中,包括表达 MAGE-A3 抗原的实体瘤; HSV-2 阳性癌症,如 GBM; CMV 阳性癌症,如 GBM;埃博拉病毒糖蛋白表达癌症等目前处于不同阶段的开发中,包括通过临床试验阶段 I/IIa/IIb/III 的临床前研究,这家生物技术公司可能会永远改变我们治疗某些类型恶性肿瘤的方式!

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Turnstone biologics

Turnstone biologics

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